Peptide Synthesis

Peptide synthesis is our business at AAPPTec.  We offer over 2300 synthetic peptides in our PEPTIDE CATALOG with many new peptides added regularly.  In addition, we perform CUSTOM PEPTIDE SYNTHESIS for our customers.  We can provide cGMP peptide synthesis of API and Cosmetic peptides at reasonable prices.

For our customers who prefer to perform their peptide synthesis, AAPPTec provides all of the materials and equipment for peptide preparation.  From peptide synthesis instruments, through HPLC systems and columns for analysis and purification to lyophilizers for isolating the purified peptides,  AAPPTec can provide all of the neccessary equipment for a functional peptide synthesis laboratory.

AAPPTec also is a supplier of the highest quality raw materials for peptide synthesis.  We supply high purity reagents, including TFA, piperidine, and peptide synthesis solvents in addition to peptide coupling reagents and protection reagents.  Our Fmoc-amino acids and Boc-amino acids are typically greater than 99.5% pure chemically and greater than 99.9% optically pure.  AAPPTec resins for solid phase peptide synthesis are 100-200 mesh beads with no small, misshapen or broken particles. 

AAPPTec offers the latest products for preparing high quality functional peptides, including pseudoproline dipeptides, isoacyl dipeptides, beta-homo-amino acids, N-methyl amino acids, and building blocks for Click chemistry and stapled peptides.  AAPPTec reagents are available in bulk as well as research quantities.  Please send an e-mail to for a quotation on bulk amounts.

AAPPTec also provides technical resources, ranging from peptide synthesis procedures on-line to technical advice from our experienced staff.  Peptide News, AAPPTec's monthly news letter, highlights recent reports of interest to peptide users and peptide chemists.

AAPPTec is the one source for peptide synthesis and peptide synthesis products. 

  • Quantities and Prices

    To obtain a quotation for custom peptide synthesis, click HERE or contact AAPPTec by e-mail at
  • Contact Us

    United States Contact Information

    Thank you for visiting our website and for your interest in our company! AAPPTec has a dedicated team of chemists, engineers, technical consultants, sales representatives, and customer service representatives whom are waiting to hear from you. We look forward to speaking with you and working with you on all of your peptide-related needs.

    Address: 6309 Shepherdsville Road Louisville, KY 40228-1027

    Toll-Free Telephone: (888) 692-9111

    Telephone: (502) 968-2223


    Fax: (502) 968-3338

    Business Hours: Monday-Friday, 8am-6pm EST

    AAPPTec has representative all over the world. For contact information on the representative nearest you, please go to

  • About Us

    AAPPTec, located in Louisville, KY, USA, offers custom peptides in quantities from mg to kg, in purities from crude to 98%, all at an affordable price. In addition to standard peptides, we also provide custom peptides with modifications such as cyclization, phosphorylation, acetylation, fluorescent labels, etc.

    Our Production Team has decades of experience in preparing high quality peptides, including long peptides, difficult peptides and peptides with special modifications.

    Our Customer Support Team has many years of experience in the peptide business and they are ready to help you with questions, orders, etc.

    AAPPTec continually strives to provide the latest technology, the most competitive prices and the highest standard of customer support to peptide chemists worldwide.

    We welcome your suggestions regarding our products and customer support. Please tell us how we can better serve you.

    Please send your suggestions to

  • What's News

    For upcoming shows, click HERE For the AAPPTec newletter Peptide News, click HERE For recent publications about peptides and proteins, click HERE.
  • FAQ

    1. How do I request a quote for my peptide?

    To request an instant quote, please sign up a free account with us and proceed to the peptide order page. If you do not have an account with us yet and would like to receive a quote for your peptide(s), please email us: or call us at 1-888-692-9111 and ask for a peptide service representative.

    2. What type of chemistry do you use?

    AAPPTec generally utilizes Fmoc chemistry for most peptide production.

    3. How do you generally purify your peptides?

    Our peptides are generally purified by preparative reversed phase HPLC, using trifluoroacetic acid (TFA) modified buffers at pH 2. Buffer A is 0.1 % TFA deionized water and buffer B is 0.1 % TFA in acetonitrile (ACN) at pH 2. Peptides are dissolved in either straight buffer A, or some amount of buffer B then diluted with buffer A.

    Sometimes it is necessary to use an organic polar solvent like (formic acid or acetic acid) in DMSO or DMF to aid in the dissolving of hydrophobic peptides but this is done on a case-by-case basis depending on the sequence analysis. The separation is monitored by UV at 214 nm and fractions are collected and analyzed by mass spectrometry for product identity and by reversed phase analytical HPLC for purity.

    The fractions are then lyophilized to remove the solvents. The fractions that meet the specifications of the order are then combined into one vial. Next, we run a final mass spectrum and analytical HPLC on the combined material.

AAPPTec is your one source for antibodies, custom peptides, peptide synthesis supplies and peptide synthesis equipment.